金沢大学大学院自然科学研究科物質化学専攻
金沢大学理工学域物質化学類化学コース

有機化学研究分野 宇梶研究室

  • 金沢大学

 

発表論文

 

2020

1) Discovery of a Novel Unsymmetrical Structural Class of HCV NS5A Inhibitors with Low Picomolar Antiviral Activity 

H. Nakamura, Y. Akagi, T. Terui, S. Fujioka, Y. Komoda, W. Kinoshita, K. Maeda, Y. Ukaji, T. Inaba  

Bioorg. Med. Chem. Lett. 2020, 30, 126932. DOI:org/10.1016/j.bmcl.2019.126932

2) 多点認識型含窒素複素環カルベンの開発と触媒的不斉反応への展開

 Development of multi-functional NHC catalysts bearing pyridine moiety: Application to catalytic asymmetric reactions

T. Soeta, Y. Ukaji  

有機合成化学協会誌; J. Synth. Org. Chem. Jpn. 2020, 78, 338−349. DOI:org/10.1016/j.bmcl.2019.126932

3) Orally Bioavailable HCV NS5A Inhibitors of Unsymmetrical Structural Class

H. Nakamura, S. Fujioka, T. Terui, S. Okuda, K. Kondo, Y. Tamatani, Y. Akagi, Y. Komoda, W. Kinoshita, S. Ito, K. Maeda, Y. Ukaji, T. Inaba  

Bioorg. Med. Chem. Lett. 2020, 30, 127361. DOI.org/10.1016/j.bmcl.2020.127361

4) Synthesis of 3,6-Dihydro-2H-1,2-oxazines via Dimethylsulfoxonium Methylide Addition to α,β-Unsaturated Nitrones 

M. Hasegawa, T. Suga, T. Soeta, Y. Ukaji

J. Org. Chem. 2020, 85, 11258−11264. doi.org/10.1021/acs.joc.0c01349

5) One-Shot Radical Cross Coupling Between Benzyl Alcohols and Alkenyl Halides using Ni/Ti/Mn System 

T. Suga, Y. Takahashi, Y. Ukaji

Adv. Synth. Catal. 2020, 362, 5622-5626. doi.org/10.1002/adsc.202000945

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